Optimal singular controls for VSEIR model of Tuberculosis

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Marlina Setia Sinaga, Yulita Molliq Rangkuti

2015 ICREM7 2015 - Proceedings of the 7th International Conference on Research and Education in Mathematics: Empowering Mathematical Sciences through Research and Education Conference paper Cited by 0

Abstract

The optimality singular controls of a VSEIR model of Tuberculosis are analyzed in this paper. There are controls that correspond to time-vary the vaccination and treatment schedules. A Hamiltonian (H) of the model is defined. The model is splited into separate one-dimensional problems, the so-called switching functions. The extreme occurs when a switching function disappears suddenly over an open interval. In which the derivatives of switching function must disappears suddenly and this typically allows computing such a control. The second-order of the function is not vanishing, which satisfied Legendre-Clebsh condition, and thus the controls of these kinds are called singular. In this work, our main emphasis is on a complete analysis of the optimum properties corresponding to trajectories. The result shows that vaccination control is singular, but treatment is not. This means that the model reached the optimality control for vaccination schedule, but not treatment schedule. © 2015 IEEE.

Affiliations

Department of Mathematics, Faculty of Mathematics and Natural Science, Universitas Negari Medan, UNIMED, 20221, North Sumatera, Indonesia